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1.
BMC Pregnancy Childbirth ; 21(1): 603, 2021 Sep 04.
Artículo en Inglés | MEDLINE | ID: mdl-34481455

RESUMEN

BACKGROUND: Mother and newborn skin-to-skin contact (SSC) is an immediate postpartum intervention known to improve the health of newborn and mothers alike. Albeit, there is paucity of data that explored the coverage or factors associated with SSC in Nigeria. Therefore, we aimed to explore the coverage and hierarchical nature of the factors associated with SSC among women of reproductive age in Nigeria. METHODS: The 2018 Nigeria Demographic and Health Survey (NDHS) data was used for this study. Data on 29,992 women who had ever given birth were extracted for analysis. SSC was the outcome variable as determined by women's report. A multivariable multilevel logistic regression model was used to estimate the fixed and random effects of the factors associated with SSC. Statistical significance was determined at p< 0.05. RESULTS: The coverage of SSC was approximately 12.0%. Educated women had higher odds of SSC, when compared with women with no formal education. Those who delivered through caesarean section (CS) had 88% reduction in SSC, when compared with women who had vaginal delivery (OR= 0.12; 95%CI: 0.07, 0.22). Women who delivered at health facility were 15.58 times as likely to practice SSC, when compared with those who delivered at home (OR= 15.58; 95%CI: 10.64, 22.82). Adequate ANC visits and low birth weight significantly increased the odds of SSC. Women from richest household were 1.70 times as likely to practice SSC, when compared with women from poorest household (OR= 1.70; 95%CI: 1.04, 2.79). There was 65% reduction in SSC among women with high rate of community non-use of media, when compared with women from low rate of community non-use of media (OR= 0.35; 95%CI: 0.20, 0.61). CONCLUSION: SSC coverage was low in Nigeria. Moreover, individual, household and community level factors were associated with SSC. More enlightenment should be created among women to bring to limelight the importance of SSC specifically to newborn's health.


Asunto(s)
Cuidado del Lactante/métodos , Cuidado del Lactante/estadística & datos numéricos , Relaciones Madre-Hijo/psicología , Madres/psicología , Madres/estadística & datos numéricos , Adolescente , Adulto , Femenino , Instituciones de Salud/estadística & datos numéricos , Parto Domiciliario/psicología , Parto Domiciliario/estadística & datos numéricos , Humanos , Cuidado del Lactante/psicología , Recién Nacido , Masculino , Persona de Mediana Edad , Análisis Multinivel , Nigeria , Embarazo , Piel , Factores Socioeconómicos , Encuestas y Cuestionarios , Adulto Joven
2.
Arch Dis Child Fetal Neonatal Ed ; 106(6): 603-607, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-33931396

RESUMEN

BACKGROUND: Neonatal endotracheal intubation is often associated with physiological instability. The Neonatal Resuscitation Program recommends a time-based limit (30 s) for intubation attempts in the delivery room, but there are limited physiological data to support recommendations in the neonatal intensive care unit (NICU). We aimed to determine the time to desaturation after ceasing spontaneous or assisted breathing in preterm infants undergoing elective endotracheal intubation in the NICU. METHODS: Observational study at The Royal Women's Hospital, Melbourne. A secondary analysis was performed of video recordings of neonates ≤32 weeks' postmenstrual age undergoing elective intubation. Infants received premedication including atropine, a sedative and muscle relaxant. Apnoeic oxygenation time (AOT) was defined as the time from the last positive pressure or spontaneous breath until desaturation (SpO2 <90%). RESULTS: Seventy-eight infants were included. The median (IQR) gestational age at birth was 27 (26-29) weeks and birth weight 946 (773-1216) g. All but five neonates desaturated to SpO2 <90% (73/78, 94%). The median (IQR) AOT was 22 (14-32) s. The median (IQR) time from ceasing positive pressure ventilation to desaturation <80% was 35 (24-44) s and to desaturation <60% was 56 (42-68) s. No episodes of bradycardia were seen. CONCLUSIONS: This is the first study to report AOT in preterm infants. During intubation of preterm infants in the NICU, desaturation occurs quickly after cessation of positive pressure ventilation. These data are important for the development of clinical guidelines for neonatal intubation. TRIAL REGISTRATION NUMBER: ACTRN12614000709640.


Asunto(s)
Apnea , Hipoxia , Cuidado del Lactante , Recien Nacido Prematuro/fisiología , Intubación Intratraqueal , Resucitación , Apnea/diagnóstico , Apnea/fisiopatología , Apnea/terapia , Australia/epidemiología , Femenino , Edad Gestacional , Humanos , Hipoxia/diagnóstico , Hipoxia/terapia , Cuidado del Lactante/métodos , Cuidado del Lactante/normas , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Unidades de Cuidado Intensivo Neonatal/estadística & datos numéricos , Intubación Intratraqueal/efectos adversos , Intubación Intratraqueal/métodos , Intubación Intratraqueal/estadística & datos numéricos , Masculino , Evaluación de Procesos y Resultados en Atención de Salud , Selección de Paciente , Respiración con Presión Positiva/métodos , Premedicación/métodos , Resucitación/métodos , Resucitación/normas , Resucitación/estadística & datos numéricos , Grabación en Video/métodos , Grabación en Video/estadística & datos numéricos
3.
PLoS One ; 16(5): e0250702, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33945560

RESUMEN

Home birth is very common in the Peruvian Amazon. In rural areas of the Loreto region, home to indigenous populations such as the Kukama-Kukamiria, birth takes place at home constantly. This study aims to understand the preference for home births as well as childbirth and newborn care practices among Kukama-Kukamiria women in rural Loreto. Following a case study approach, sixty semi-structured, face-to-face interviews were conducted with recent mothers who experienced childbirth within one year prior to the interview, female relatives of recent mothers who had a role in childbirth, male relatives of recent mothers, community health workers, and traditional healers. We found that for women from these communities, home birth is a courageous act and an intimate (i.e. members of the community and relatives participate in it) and inexpensive practice in comparison with institutional birth. These preferences are also linked to experiences of mistreatment at health facilities, lack of cultural adaptation of birthing services, and access barriers to them. Preparations for home births included handwashing and cleaning delivery surfaces. After birth, waiting for the godparent to arrive to cut the cord can delay drying of the newborn. Discarding of colostrum, lack of skin-to-skin contact as well as a range of responses regarding immediate breastfeeding and immediate drying of the baby were also found. These findings were used to tailor the educational content of the Mamas del Rio program, where community health workers are trained to identify pregnancy early, perform home visits to pregnant women and newborns, and promote essential newborn care practices in case institutional birth is not desired or feasible. We make recommendations to improve Peru's cultural adaptation of birthing services.


Asunto(s)
Parto Domiciliario/estadística & datos numéricos , Cuidado del Lactante/estadística & datos numéricos , Parto , Población Rural/estadística & datos numéricos , Adulto , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Recién Nacido , Perú , Embarazo , Factores Socioeconómicos , Adulto Joven
4.
J Nurs Meas ; 29(2): 334-346, 2021 08 01.
Artículo en Inglés | MEDLINE | ID: mdl-33795487

RESUMEN

BACKGROUND AND PURPOSE: An exploratory latent class analysis (LCA) was performed assessing the association between maternity waiting home (MWH) use and maternal-newborn care knowledge. METHODS: A two-group comparison design using a face-to-face interview (n = 250) was conducted to understand if MWH use was associated with greater maternal knowledge of newborn care. RESULTS: High levels of maternal knowledge of newborn care were associated with MWH use. Mothers with low levels of knowledge were less likely to use an MWH prior to delivery and more likely to have fewer pregnancies, attend less than four antenatal care (ANC) visits, and receive no education about newborn health problems during ANC. CONCLUSIONS: Nurses need to target younger, primigravida mothers attending fewer ANC visits with educational opportunities while advocating for expansion of health education at MWHs to potentiate long-term benefits for improved maternal-newborn health and delivery outcomes.


Asunto(s)
Cuidado del Lactante/psicología , Servicios de Salud Materna/estadística & datos numéricos , Mujeres Embarazadas/educación , Mujeres Embarazadas/psicología , Atención Prenatal/psicología , Atención Prenatal/estadística & datos numéricos , Población Rural/estadística & datos numéricos , Adulto , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Análisis de Clases Latentes , Embarazo , Reproducibilidad de los Resultados , Zambia
5.
Am J Perinatol ; 38(7): 741-746, 2021 06.
Artículo en Inglés | MEDLINE | ID: mdl-33853145

RESUMEN

OBJECTIVE: This study aimed to describe maternal characteristics and clinical outcomes of infants born to mothers with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tests during pregnancy at an urban, safety-net hospital in Boston. STUDY DESIGN: We abstracted electronic chart data from 75 pregnant women with positive SARS-CoV-2 tests at any stage of gestation until 72 hours after birth who delivered consecutively between March 31 and August 6, 2020 at our center. We collected clinical data on maternal and infant characteristics, including testing, signs, and symptoms of coronavirus disease 2019 (COVID-19), delivery outcomes, newborn care practices (skin-to-skin care, location of care, and breastfeeding) and 30-day postdischarge infant emergency room visits and readmissions. We described categorical characteristics as percentages for this case series. RESULTS: Among 75 pregnant women, 47 (63%) were Hispanic, 10 (13%) had hypertension, 23 (30%) had prepregnancy obesity, and 57 (76%) had symptomatic SARS-CoV-2 infection. Regarding birth outcomes, 32 (41%) had cesarean delivery and 14 (19%) had preterm birth. Among 75 infants, 5 (7%) had positive SARS-CoV-2 polymerase chain reaction tests in the first week of life, all of whom were born to Hispanic mothers with symptomatic SARS-CoV-2 infection and had clinical courses consistent with gestational age. Six (8%) infants visited the emergency department within 30 days of discharge; one was admitted with a non-COVID-19 diagnosis. CONCLUSION: At our urban, safety-net hospital among pregnant women with positive SARS-CoV-2 tests, 41% had a cesarean delivery and 19% had a preterm birth. Seven percent of infants had one or more positive SARS-CoV-2 tests and all infants had clinical courses expected for gestational age. KEY POINTS: · Among 75 pregnant women with SARS-CoV-2 positive testing at our center, five infants (7%) had one or more SARS-CoV-2 positive tests in the first week of life.. · Infants with positive SARS-CoV-2 tests had clinical courses expected for gestational age..


Asunto(s)
COVID-19 , Enfermedades del Recién Nacido , Transmisión Vertical de Enfermedad Infecciosa , Complicaciones Infecciosas del Embarazo , SARS-CoV-2/aislamiento & purificación , Adulto , Boston/epidemiología , COVID-19/epidemiología , COVID-19/terapia , COVID-19/transmisión , Cesárea/estadística & datos numéricos , Femenino , Edad Gestacional , Hospitalización/estadística & datos numéricos , Humanos , Cuidado del Lactante/métodos , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Enfermedades del Recién Nacido/epidemiología , Enfermedades del Recién Nacido/virología , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/estadística & datos numéricos , Embarazo , Complicaciones Infecciosas del Embarazo/epidemiología , Complicaciones Infecciosas del Embarazo/terapia , Resultado del Embarazo , Nacimiento Prematuro/epidemiología , Proveedores de Redes de Seguridad/estadística & datos numéricos
6.
BMJ Glob Health ; 6(3)2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-33716220

RESUMEN

INTRODUCTION: The COVID-19 pandemic is disrupting health systems globally. Maternity care disruptions have been surveyed, but not those related to vulnerable small newborns. We aimed to survey reported disruptions to small and sick newborn care worldwide and undertake thematic analysis of healthcare providers' experiences and proposed mitigation strategies. METHODS: Using a widely disseminated online survey in three languages, we reached out to neonatal healthcare providers. We collected data on COVID-19 preparedness, effects on health personnel and on newborn care services, including kangaroo mother care (KMC), as well as disruptors and solutions. RESULTS: We analysed 1120 responses from 62 countries, mainly low and middle-income countries (LMICs). Preparedness for COVID-19 was suboptimal in terms of guidelines and availability of personal protective equipment. One-third reported routine testing of all pregnant women, but 13% had no testing capacity at all. More than 85% of health personnel feared for their own health and 89% had increased stress. Newborn care practices were disrupted both due to reduced care-seeking and a compromised workforce. More than half reported that evidence-based interventions such as KMC were discontinued or discouraged. Separation of the mother-baby dyad was reported for both COVID-positive mothers (50%) and those with unknown status (16%). Follow-up care was disrupted primarily due to families' fear of visiting hospitals (~73%). CONCLUSION: Newborn care providers are stressed and there is lack clarity and guidelines regarding care of small newborns during the pandemic. There is an urgent need to protect life-saving interventions, such as KMC, threatened by the pandemic, and to be ready to recover and build back better.


Asunto(s)
COVID-19/prevención & control , Personal de Salud/estadística & datos numéricos , Cuidado del Lactante , Lactancia Materna , Estudios Transversales , Femenino , Humanos , Cuidado del Lactante/métodos , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Método Madre-Canguro , Pandemias , Embarazo , SARS-CoV-2 , Encuestas y Cuestionarios
7.
Arch Argent Pediatr ; 119(2): 76-82, 2021 04.
Artículo en Inglés, Español | MEDLINE | ID: mdl-33749192

RESUMEN

INTRODUCTION: The objective of this study was to analyze available resources, guidelines in use, and preparedness to care for newborn infants at maternity centers in Argentina during the COVID-19 pandemic. METHOD: Cross-sectional study based on a survey administered to medical and nursing staff. In May 2020, Argentine facilities with more than 500 annual births were contacted; 58 % of these were from the public sector. RESULTS: In total, 104/147 facilities answered (71 %). All had guidelines for care during the pandemic, and 93 % indicated they had been trained on how to use them. A companion was not allowed during childbirth in 26 % of private facilities and in 60 % of public ones (p < 0.01). Deferred cord clamping was recommended in 87 %; rooming-in with asymptomatic newborns was promoted in 62 %; breastfeeding using protective measures was recommended in 70 %; and breast milk using a bottle, in 23 %. In 94 %, family visiting in the Neonatology Unit was restricted. Difficulties included the unavailability of individual rooms for symptomatic newborn infants and a potential shortage of health care staff and personal protective equipment. CONCLUSIONS: All facilities are aware of the national guidelines to fight the pandemic. Most have the resources to comply with the recommended protective measures. There is uncertainty as to whether personal protective equipment, staff, and physical space available at the different facilities would be enough if cases increased significantly.


Introducción. El objetivo de este estudio fue analizar recursos disponibles, guías utilizadas y preparación para la atención de neonatos en maternidades de Argentina durante la pandemia de COVID-19. Método. Estudio transversal mediante una encuesta enviada a equipos médicos y de enfermería. En mayo de 2020, se contactaron instituciones de más de 500 nacimientos anuales en la Argentina, el 58 % del sector público. Resultados. Respondieron 104/147 instituciones (el 71 %). Todas contaban con guías para la atención durante la pandemia, y un 93 % refirió haber recibido capacitación para su uso. No autorizaban la presencia de acompañante en el parto el 26 % de instituciones privadas y el 60 % de las públicas (p < 0,01). El 87 % recomendaba ligadura oportuna del cordón, el 62 % promovía internación conjunta en neonatos asintomáticos, un 70 % recomendaba la puesta al pecho con medidas de protección, y el 23 %, leche materna mediante biberón. El 94 % restringía el ingreso de familiares a Neonatología. Las dificultades incluyeron imposibilidad de contar con habitaciones individuales para neonatos sintomáticos y potencial limitación del personal de salud y equipos de protección personal. Conclusiones. Todas las instituciones conocen las guías nacionales para enfrentar la pandemia. La mayoría cuenta con recursos para respetar las medidas de protección recomendadas. Existe incertidumbre sobre si, ante un aumento significativo en el número de casos, serán suficientes los elementos de protección personal, el personal y el espacio físico disponible en los distintos centros.


Asunto(s)
COVID-19/prevención & control , Recursos en Salud/provisión & distribución , Cuidado del Lactante/organización & administración , Control de Infecciones/organización & administración , Servicios de Salud Materna/organización & administración , Argentina/epidemiología , COVID-19/epidemiología , Estudios Transversales , Femenino , Encuestas de Atención de la Salud , Política de Salud , Humanos , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Control de Infecciones/instrumentación , Control de Infecciones/métodos , Control de Infecciones/estadística & datos numéricos , Masculino , Servicios de Salud Materna/estadística & datos numéricos , Pandemias , Equipo de Protección Personal/provisión & distribución , Guías de Práctica Clínica como Asunto , Embarazo
8.
BMC Pregnancy Childbirth ; 21(Suppl 1): 229, 2021 Mar 26.
Artículo en Inglés | MEDLINE | ID: mdl-33765948

RESUMEN

BACKGROUND: An estimated 30 million neonates require inpatient care annually, many with life-threatening infections. Appropriate antibiotic management is crucial, yet there is no routine measurement of coverage. The Every Newborn Birth Indicators Research Tracking in Hospitals (EN-BIRTH) study aimed to validate maternal and newborn indicators to inform measurement of coverage and quality of care. This paper reports validation of reported antibiotic coverage by exit survey of mothers for hospitalized newborns with clinically-defined infections, including sepsis, meningitis, and pneumonia. METHODS: EN-BIRTH study was conducted in five hospitals in Bangladesh, Nepal, and Tanzania (July 2017-July 2018). Neonates were included based on case definitions to focus on term/near-term, clinically-defined infection syndromes (sepsis, meningitis, and pneumonia), excluding major congenital abnormalities. Clinical management was abstracted from hospital inpatient case notes (verification) which was considered as the gold standard against which to validate accuracy of women's report. Exit surveys were conducted using questions similar to The Demographic and Health Surveys (DHS) approach for coverage of childhood pneumonia treatment. We compared survey-report to case note verified, pooled across the five sites using random effects meta-analysis. RESULTS: A total of 1015 inpatient neonates admitted in the five hospitals met inclusion criteria with clinically-defined infection syndromes. According to case note verification, 96.7% received an injectable antibiotic, although only 14.5% of them received the recommended course of at least 7 days. Among women surveyed (n = 910), 98.8% (95% CI: 97.8-99.5%) correctly reported their baby was admitted to a neonatal ward. Only 47.1% (30.1-64.5%) reported their baby's diagnosis in terms of sepsis, meningitis, or pneumonia. Around three-quarters of women reported their baby received an injection whilst in hospital, but 12.3% reported the correct antibiotic name. Only 10.6% of the babies had a blood culture and less than 1% had a lumbar puncture. CONCLUSIONS: Women's report during exit survey consistently underestimated the denominator (reporting the baby had an infection), and even more so the numerator (reporting known injectable antibiotics). Admission to the neonatal ward was accurately reported and may have potential as a contact point indicator for use in household surveys, similar to institutional births. Strengthening capacity and use of laboratory diagnostics including blood culture are essential to promote appropriate use of antibiotics. To track quality of neonatal infection management, we recommend using inpatient records to measure specifics, requiring more research on standardised inpatient records.


Asunto(s)
Antibacterianos/uso terapéutico , Cuidado del Lactante/estadística & datos numéricos , Meningitis Bacterianas/tratamiento farmacológico , Sepsis Neonatal/tratamiento farmacológico , Neumonía Bacteriana/tratamiento farmacológico , Bangladesh/epidemiología , Utilización de Medicamentos/estadística & datos numéricos , Femenino , Hospitalización/estadística & datos numéricos , Humanos , Cuidado del Lactante/organización & administración , Recién Nacido , Masculino , Meningitis Bacterianas/epidemiología , Sepsis Neonatal/epidemiología , Nepal/epidemiología , Neumonía Bacteriana/epidemiología , Embarazo , Indicadores de Calidad de la Atención de Salud/estadística & datos numéricos , Encuestas y Cuestionarios/estadística & datos numéricos , Tanzanía/epidemiología , Adulto Joven
9.
Reprod Health ; 18(1): 50, 2021 Feb 27.
Artículo en Inglés | MEDLINE | ID: mdl-33639966

RESUMEN

BACKGROUND: We aim to assess competencies (knowledge, skills and attitudes) of midwifery care providers as well as their experiences and perceptions of in-service training in the four study countries; Benin, Malawi, Tanzania and Uganda as part of the Action Leveraging Evidence to Reduce perinatal mortality and morbidity in sub-Saharan Africa project (ALERT). While today more women in low- and middle-income countries give birth in health care facilities, reductions in maternal and neonatal mortality have been less than expected. This paradox may be explained by the standard and quality of intrapartum care provision which depends on several factors such as health workforce capacity and the readiness of the health system as well as access to care. METHODS: Using an explanatory sequential mixed method design we will employ three methods (i) a survey will be conducted using self-administered questionnaires assessing knowledge, (ii) skills drills assessing basic intrapartum skills and attitudes, using an observation checklist and (iii) Focus Group Discussions (FGDs) to explore midwifery care providers' experiences and perceptions of in-service training. All midwifery care providers in the study facilities are eligible to participate in the study. For the skills drills a stratified sample of midwifery care providers will be selected in each hospital according to the number of providers and, professional titles and purposive sampling will be used for the FGDs. Descriptive summary statistics from the survey and skills drills will be presented by country. Conventional content analysis will be employed for data analysis of the FGDs. DISCUSSION: We envision comparative insight across hospitals and countries. The findings will be used to inform a targeted quality in-service training and quality improvement intervention related to provision of basic intrapartum care as part of the ALERT project. TRIAL REGISTRATION: PACTR202006793783148-June 17th, 2020.


Asunto(s)
Actitud del Personal de Salud , Competencia Clínica , Partería , Obstetricia/normas , Calidad de la Atención de Salud , Adulto , Benin/epidemiología , Lista de Verificación , Competencia Clínica/normas , Competencia Clínica/estadística & datos numéricos , Parto Obstétrico/enfermería , Parto Obstétrico/normas , Parto Obstétrico/estadística & datos numéricos , Femenino , Grupos Focales , Conocimientos, Actitudes y Práctica en Salud , Personal de Salud/normas , Personal de Salud/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/normas , Humanos , Cuidado del Lactante/normas , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Malaui/epidemiología , Partería/educación , Partería/normas , Partería/estadística & datos numéricos , Obstetricia/estadística & datos numéricos , Embarazo , Encuestas y Cuestionarios , Tanzanía/epidemiología , Uganda/epidemiología , Adulto Joven
10.
JAMA Netw Open ; 3(9): e2018119, 2020 09 01.
Artículo en Inglés | MEDLINE | ID: mdl-32965499

RESUMEN

Importance: In very preterm newborns, gut microbiota is highly variable with major dysbiosis. Its association with short-term health is widely studied, but the association with long-term outcomes remains unknown. Objective: To investigate in preterm newborns the associations among practice strategies in neonatal intensive care units (NICUs), gut microbiota, and outcomes at 2 years. Design, Setting, and Participants: EPIFLORE is a prospective observational cohort study that includes a stool sample collection during the fourth week after birth. Preterm newborns of less than 32 weeks of gestational age (GA) born in 2011 were included from 24 NICUs as part of the French nationwide population-based cohort, EPIPAGE 2. Data were collected from May 2011 to December 2011 and analyzed from September 2016 to December 2018. Exposures: Eight NICU strategies concerning sedation, ventilation, skin-to-skin practice, antibiotherapy, ductus arteriosus, and breastfeeding were assessed. A NICU was considered favorable to a practice if the percentage of that practice in the NICU was more than the expected percentage. Main Outcomes and Measures: Gut microbiota was analyzed by 16S ribosomal RNA gene sequencing and characterized by a clustering-based method. The 2-year outcome was defined by death or neurodevelopmental delay using a Global Ages and Stages questionnaire score. Results: Of 577 newborns included in the study, the mean (SD) GA was 28.3 (2.0) weeks, and 303 (52.5%) were male. Collected gut microbiota was grouped into 5 discrete clusters. A sixth cluster included nonamplifiable samples owing to low bacterial load. Cluster 4 (driven by Enterococcus [n = 63]), cluster 5 (driven by Staphylococcus [n = 52]), and cluster 6 (n = 93) were significantly associated with lower mean (SD) GA (26.7 [1.8] weeks and 26.8 [1.9] weeks, respectively) and cluster 3 (driven by Escherichia/Shigella [n = 61]) with higher mean (SD) GA (29.4 [1.6] weeks; P = .001). Cluster 3 was considered the reference. After adjustment for confounders, no assisted ventilation at day 1 was associated with a decreased risk of belonging to cluster 5 or cluster 6 (adjusted odds ratio [AOR], 0.21 [95% CI, 0.06-0.78] and 0.19 [95% CI, 0.06-0.62], respectively) when sedation (AOR, 10.55 [95% CI, 2.28-48.87] and 4.62 [1.32-16.18], respectively) and low volume of enteral nutrition (AOR, 10.48 [95% CI, 2.48-44.29] and 7.28 [95% CI, 2.03-26.18], respectively) was associated with an increased risk. Skin-to-skin practice was associated with a decreased risk of being in cluster 5 (AOR, 0.14 [95% CI, 0.04-0.48]). Moreover, clusters 4, 5, 6 were significantly associated with 2-year nonoptimal outcome (AOR, 6.17 [95% CI, 1.46-26.0]; AOR, 4.53 [95% CI, 1.02-20.1]; and AOR, 5.42 [95% CI, 1.36-21.6], respectively). Conclusions and Relevance: Gut microbiota of very preterm newborns at week 4 is associated with NICU practices and 2-year outcomes. Microbiota could be a noninvasive biomarker of immaturity.


Asunto(s)
Disbiosis/fisiopatología , Microbioma Gastrointestinal/fisiología , Recien Nacido Extremadamente Prematuro/crecimiento & desarrollo , Enfermedades del Prematuro/microbiología , Trastornos del Neurodesarrollo/epidemiología , Preescolar , Femenino , Humanos , Lactante , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Masculino , Trastornos del Neurodesarrollo/microbiología , Estudios Prospectivos
11.
J Pediatr ; 226: 64-70, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32791077

RESUMEN

OBJECTIVE: To assess the impact of separation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR)-positive mother-newborn dyads on breastfeeding outcomes. STUDY DESIGN: This observational longitudinal cohort study of mothers with SARS-CoV-2 PCR-and their infants at 3 NYU Langone Health hospitals was conducted between March 25, 2020, and May 30, 2020. Mothers were surveyed by telephone regarding predelivery feeding plans, in-hospital feeding, and home feeding of their neonates. Any change prompted an additional question to determine whether this change was due to coronavirus disease-2019 (COVID-19). RESULTS: Of the 160 mother-newborn dyads, 103 mothers were reached by telephone, and 85 consented to participate. There was no significant difference in the predelivery feeding plan between the separated and unseparated dyads (P = .268). Higher rates of breastfeeding were observed in the unseparated dyads compared with the separated dyads both in the hospital (P < .001) and at home (P = .012). Only 2 mothers in each group reported expressed breast milk as the hospital feeding source (5.6% of unseparated vs 4.1% of separated). COVID-19 was more commonly cited as the reason for change in the separated group (49.0% vs 16.7%; P < .001). When the dyads were further stratified by symptom status into 4 groups-asymptomatic separated, asymptomatic unseparated, symptomatic separated, and symptomatic unseparated-the results remained unchanged. CONCLUSIONS: In the setting of COVID-19, separation of mother-newborn dyads impacts breastfeeding outcomes, with lower rates of breastfeeding both during hospitalization and at home following discharge compared with unseparated mothers and infants. No evidence of vertical transmission was observed; 1 case of postnatal transmission occurred from an unmasked symptomatic mother who held her infant at birth.


Asunto(s)
Lactancia Materna/estadística & datos numéricos , COVID-19/prevención & control , Cuidado del Lactante/métodos , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Conducta Materna , Complicaciones Infecciosas del Embarazo/diagnóstico , Adolescente , Adulto , Lactancia Materna/psicología , COVID-19/diagnóstico , COVID-19/psicología , COVID-19/transmisión , Prueba de Ácido Nucleico para COVID-19 , Femenino , Hospitalización , Humanos , Cuidado del Lactante/psicología , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Transmisión Vertical de Enfermedad Infecciosa/estadística & datos numéricos , Estimación de Kaplan-Meier , Estudios Longitudinales , Masculino , Embarazo , Adulto Joven
12.
BMC Public Health ; 20(1): 1245, 2020 Aug 17.
Artículo en Inglés | MEDLINE | ID: mdl-32807128

RESUMEN

BACKGROUND: Despite concerted global efforts towards achieving infant-survival, infant mortality lingers as a problem in developing countries. Environmental and personal-level factors are assumed to account for this situation. This study was undertaken to provide better understanding of the dynamics of predictors of infant-survival practices among mothers with infants attending paediatric clinics. METHODS: A cross-sectional survey design was adopted. Data was collected from 386 nursing mothers selected by convenience sampling. Interviewer-administered questionnaires were used for data collection. The questionnaire consisted of 38-items including demographic information of respondents, health-literacy counsels received during antenatal care, social-support from significant others, and self-efficacy to carry-out infant-survival instructions. Responses were transformed into rating scales for each variable and data analysis was conducted by linear regression analysis with test of hypotheses at 5% level of significance. RESULTS: The mean age of respondents was 29.8 ± 5.8 years. Majority (81.6%) were married. Yorubas (83.90%) were predominant. Participants had mean scores of 10.50 ± 3.83, 10.56 ± 3.70 and 16.61 ± 4.56 respectively computed for levels of health-literacy, social-support, and self-efficacy. The dependent variable measured level of infant-survival practices and respondents scored 16.53 ± 4.71. The study found a significant association among variables. Self-efficacy was the major predictor variable of self-reported infant-survival practices (R = 0.466; R2 = 0.217; P<0.05). CONCLUSION: We conclude that participants had average levels of health-literacy, social-support, self-efficacy, and infant-survival practices. Healthcare providers should make efforts to empower pregnant women on activities essential for infant-survival. Family members of nursing mothers should as well be knowledgeable about the advantages of supporting them.


Asunto(s)
Alfabetización en Salud , Cuidado del Lactante/psicología , Madres/psicología , Autoeficacia , Apoyo Social , Adulto , Instituciones de Atención Ambulatoria , Lactancia Materna/psicología , Lactancia Materna/estadística & datos numéricos , Estudios Transversales , Femenino , Humanos , Lactante , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Modelos Lineales , Madres/estadística & datos numéricos , Nigeria , Embarazo , Atención Prenatal/psicología , Atención Prenatal/estadística & datos numéricos , Encuestas y Cuestionarios , Adulto Joven
15.
Rev. chil. pediatr ; 91(4): 529-535, ago. 2020. tab
Artículo en Español | LILACS | ID: biblio-1138667

RESUMEN

INTRODUCCIÓN: La Academia Americana de Pediatría recomienda que los lactantes menores de un año duerman en posición supina para prevenir el síndrome de muerte súbita en lactantes (SMSL). OBJETIVO: Describir la posición en que duermen un grupo de lactantes y factores de riesgo asociados al SMSL. SUJETOS Y MÉTODO: Estudio piloto, prospectivo concurrente, de lactantes < 45 días de vida en control sano en Centro Médico San Joaquín UC Christus. Criterios de exclusión: prematurez (edad gestacional < 37 semanas) y patología de base (respiratorias, metabólicas, cardiológicas). Se aplicó encuesta al cuidador principal respecto a datos demográficos y hábitos de sueño, basada en encuesta BISQ (Brief Screening Questionnaire for Infant Sleep Problems) validada en español, dado la inexistencia de instru mentos para < 3 meses. RESULTADOS: Se obtuvo muestra de 100 lactantes de edad 16,78 ± 12,88 días de vida, siendo 57% mujeres. La madre fue el principal informante (84%). El 79% de los lactantes dor mían en decúbito supino, 19% lo hacía de lado y 2% en prono. El 66% dormía en cuna en habitación de los padres, 31% en la cama de los padres. El 74% se quedaban dormidos durante la alimentación. El 28% de los lactantes estaban expuestos a tabaquismo pasivo. El 91% cuidadores estaba informa do sobre la posición segura de sueño, siendo el principal informante el pediatra (54%). CONCLUSIONES: En esta muestra se encontró alto porcentaje de lactantes < 45 días que duermen en posición no segura, siendo frecuente el colecho. Es importante implementar campañas locales de prevención del SMSL que refuercen el hábito de dormir seguro.


INTRODUCTION: The American Academy of Pediatrics recommends, through the implementation of the "Back to Sleep (BTS)" campaign, the supine sleeping position for infant sleeping since it prevents to prevent Sudden Infant Death Syndrome (SIDS). OBJECTIVE: To describe the sleeping position of a group of infants and the risk factors associated with sudden infant death syndrome (SIDS). SUBJECTS AND METHOD: Prospective pilot study, including infants < 45 days of life in well-child care visits at a medical center. Exclusion criteria: Preterm-born infant (gestational age < 37 weeks) and/or comorbidities (pulmonary, metabolic, cardiologic). A brief parental questionnaire was conducted regarding general demographic data and sleep habits. The questioner was based on the BISQ - Spanish version, due to the lack of validated instruments for infants < 3-month-old. RESULTS: We included a sample of 100 infants between 16.78 ± 12.88 days old (57% girls). Mothers were the main information source (84%). 79% of the infants slept in supine position, 19% slept on their sides, and 2% in prone position. Regarding the place where the infants slept, 66% did in their crib in the parents' room and 31% slept in parents' bed. 74% of infants fell asleep while being fed. 28% of infants were exposed to passive smoking at home. 91% of parents were informed about safe sleep positions, reporting that pediatricians were the main source of information (54%). CONCLUSION: We found a high percentage of infants < 45 days of life who slept in an unsafe position, and frequently co-sleep with their parents. Thus, it is important to implement local SIDS prevention campaigns to reinforce safe infant sleep.


Asunto(s)
Humanos , Masculino , Femenino , Recién Nacido , Lactante , Sueño , Muerte Súbita del Lactante/etiología , Muerte Súbita del Lactante/prevención & control , Posición Supina , Cuidado del Lactante/métodos , Modelos Logísticos , Chile , Proyectos Piloto , Estudios Prospectivos , Factores de Riesgo , Guías de Práctica Clínica como Asunto , Factores Protectores , Cuidado del Lactante/normas , Cuidado del Lactante/estadística & datos numéricos
16.
Midwifery ; 90: 102804, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32721638

RESUMEN

OBJECTIVE: To examine the association between type of birth attendant and early newborn care in Senegal. DESIGN: This was a secondary analysis of cross-sectional data from the 2017 Continuous Demographic and Health Survey. PARTICIPANTS: The study included data on 6328 women with live births in the three years preceding the survey. MEASUREMENTS: The main exposure was the type of birth attendant (doctor, nurse/midwife, auxiliary midwife/matrone, traditional birth attendant, or "others (friend, relative, or no one)). We assessed three outcomes: 1) early initiation of breastfeeding, 2) breastfeeding support, and 3) cord examination. We used multivariable logistic regression to estimate the odds ratios and 95% confidence intervals of early newborn care after adjusting for potential confounders. FINDINGS: The coverage of all three newborn care indicators of interest was low. In the adjusted regression models, women whose births were assisted by a nurse/midwife were nearly twice as likely to initiate breastfeeding early compared to those assisted by doctors (odds ratio: 1.87, 95% confidence interval: 1.00-3.45). Women assisted at birth by doctors were significantly more likely to report breastfeeding support and newborn cord examination than those assisted by other types of birth attendants. CONCLUSIONS AND IMPLICATIONS FOR PRACTICE: Although most recent births were facility-based and assisted by skilled birth attendants, the prevalence of early newborn care was suboptimal. This presents a missed opportunity to improve neonatal outcomes. Training and supporting skilled birth attendants may bridge the gap between opportunity and practice, and lead to improved coverage and quality of newborn care in Senegal.


Asunto(s)
Cuidado del Lactante/métodos , Partería/normas , Adolescente , Adulto , Estudios Transversales , Femenino , Humanos , Cuidado del Lactante/normas , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Masculino , Persona de Mediana Edad , Partería/estadística & datos numéricos , Oportunidad Relativa , Embarazo , Senegal
17.
J Obstet Gynecol Neonatal Nurs ; 49(5): 416-422, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32553591

RESUMEN

Postpartum depression is one of the most common complications of childbirth, and another is pain. A growing body of research shows that the severity and duration of postpartum pain can increase a woman's risk for postpartum depression. Postpartum depression and pain negatively affect maternal well-being, and postpartum depression has been associated with adverse outcomes in children. However, there is a dearth of information about the effects of postpartum depression and pain on infant care and development. The objectives of this commentary were to highlight the need to address this gap in the literature, offer a preliminary conceptual model to advance the field, and ignite new lines of inquiry to inform infant care and development.


Asunto(s)
Depresión Posparto/complicaciones , Cuidado del Lactante/normas , Recién Nacido/crecimiento & desarrollo , Dolor/complicaciones , Periodo Posparto/psicología , Adulto , Depresión Posparto/psicología , Femenino , Humanos , Lactante , Cuidado del Lactante/métodos , Cuidado del Lactante/estadística & datos numéricos , Relaciones Madre-Hijo/psicología , Dolor/psicología , Periodo Posparto/efectos de los fármacos
18.
BMC Pregnancy Childbirth ; 20(1): 287, 2020 May 12.
Artículo en Inglés | MEDLINE | ID: mdl-32397969

RESUMEN

BACKGROUND: Neonatal mortality rate in Kenya continues to be unacceptably high. In reducing newborn deaths, inequality in access to care and quality care have been identified as current barriers. Contributing to these barriers are the bypassing behaviour and geographical access which leads to delay in seeking newborn care. This study (i) measured geographical accessibility of inpatient newborn care, and (ii), characterized bypassing behaviour using the geographical accessibility of the inpatient newborn care seekers. METHODS: Geographical accessibility to the inpatient newborn units was modelled based on travel time to the units across Bungoma County. Data was then collected from 8 inpatient newborn units and 395 mothers whose newborns were admitted in the units were interviewed. Their spatial residence locations were geo-referenced and were used against the modelled travel time to define bypassing behaviour. RESULTS: Approximately 90% of the sick newborn population have access to nearest newborn units (< 2 h). However, 36% of the mothers bypassed their nearest inpatient newborn facility, with lack of diagnostic services (28%) and distrust of health personnel (37%) being the major determinants for bypassing. Approximately 75% of the care seekers preferred to use the higher tier facilities for both maternal and neonatal care in comparison to sub-county facilities which mostly were bypassed and remained underutilised. CONCLUSION: Our findings suggest that though majority of the population have access to care, sub-county inpatient newborn facilities have high risk of being bypassed. There is need to improve quality of care in maternal care, to reduce bypassing behaviour and improving neonatal outcome.


Asunto(s)
Instituciones de Salud/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Cuidado del Lactante/estadística & datos numéricos , Aceptación de la Atención de Salud/estadística & datos numéricos , Adulto , Femenino , Sistemas de Información Geográfica , Geografía , Humanos , Lactante , Mortalidad Infantil , Recién Nacido , Kenia , Servicios de Salud Materna , Análisis Espacial , Adulto Joven
19.
Prenat Diagn ; 40(8): 966-971, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32314369

RESUMEN

OBJECTIVES: Critical pulmonary stenosis (PS) and pulmonary atresia with intact ventricular septum (PAIVS) require urgent neonatal intervention. Since PS may be more insidious than PAIVS during gestation, we hypothesized that neonates with PS would have lower rates of prenatal detection than PAIVS. METHODS: We performed a retrospective chart review of all neonates who underwent diagnostic or interventional cardiac catheterization between 2000 and 2014 for critical PS or PAIVS. The rates of prenatal diagnosis were calculated for PS and PAIVS. Prenatal and postnatal echocardiographic data were reviewed. RESULTS: 178 patients met inclusion criteria: 91 with critical PS and 87 with PAIVS. The prenatal diagnosis rate for critical PS was lower than for PAIVS at 37% (34/91) vs 60% (52/87) (P = .003). At the time of diagnosis at a median gestational age of 25 weeks, the median TV z-score for patients with critical PS was larger than in PAIVS (-0.15 vs -3.0 P = .004). CONCLUSION: Critical PS had a lower prenatal detection rate than PAIVS, likely due to a relatively normal 4-chamber view at the time of routine second trimester screening in patients with PS. Color flow Doppler of the outflow tracts may improve detection, since outflow tracts may appear normal by 2D imaging.


Asunto(s)
Cardiopatías Congénitas/diagnóstico , Atresia Pulmonar/diagnóstico , Estenosis de la Válvula Pulmonar/diagnóstico , Ultrasonografía Prenatal/estadística & datos numéricos , Adulto , Ecocardiografía/métodos , Ecocardiografía/estadística & datos numéricos , Femenino , Cardiopatías Congénitas/epidemiología , Cardiopatías Congénitas/terapia , Humanos , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Masculino , Atención Posnatal/estadística & datos numéricos , Embarazo , Atresia Pulmonar/epidemiología , Atresia Pulmonar/terapia , Estenosis de la Válvula Pulmonar/epidemiología , Estenosis de la Válvula Pulmonar/terapia , Reproducibilidad de los Resultados , Estudios Retrospectivos , Ultrasonografía Prenatal/métodos , Estados Unidos/epidemiología
20.
Glob Health Action ; 13(1): 1748403, 2020 12 31.
Artículo en Inglés | MEDLINE | ID: mdl-32345146

RESUMEN

Background: The increasing trends in cesarean delivery are globally acknowledged. However, in many low-resource countries, socioeconomic disparities have created a pattern of underuse and overuse among lower and higher socioeconomic groups. The impact of rising cesarean delivery rates on neonatal survival is also unclear.Objective: To examine cesarean delivery and its associated socioeconomic patterns and neonatal survival outcome in Kenya and Tanzania.Methods: We employed binary logistic regression to analyze cross-sectional demographic and health survey data on neonates born in health facilities in Kenya (2014) and Tanzania (2016).Results: Cesarean delivery rates ranged from 5% among uneducated, rural Tanzanian women to 26% among educated urban women in Kenya to 37.5% among managers in urban Tanzania. Overall findings indicated higher odds of cesarean delivery among mothers from richest households, adjusted odds ratio (aOR) 1.4 (95% CI 1.2-1.8), those insured, aOR 1.6 (95% CI 1.3-1.9), highly educated, aOR 1.6 (95% CI 1.2-2.0) and managers aOR 1.7 (95% CI 1.3-2.2), compared to middle class, no insurance, primary education and unemployed, respectively. Overall, compared to normal births and while adjusting for maternal risk factors, cesarean delivery was significantly associated with neonatal mortality in Kenya and Tanzania, overall aOR 1.7 (95% CI 1.2-2.7). However, statistical significance ceased when fetal risk factors and number of antenatal care visits were further controlled for, aOR 1.6 (95% CI 0.9-2.6).Conclusion: Disproportionate access to cesarean delivery has widened in Kenya and Tanzania. Higher risks of cesarean-related neonatal deaths exist. Medically indicated or not, the safety and/or choice of cesarean delivery is best addressed on individual basis at the health-facility level. However, policy initiatives to eliminate incentives, improve equitable access and accountability to reduce unnecessary cesarean deliveries through well-informed decisions are needed. Efforts to prevent unintended pregnancies among adolescents as well as training of health workers and continuous research to improve neonatal outcomes are vital.


Asunto(s)
Cesárea/estadística & datos numéricos , Cesárea/tendencias , Cuidado del Lactante/organización & administración , Mortalidad Infantil/tendencias , Aceptación de la Atención de Salud/estadística & datos numéricos , Factores Socioeconómicos , Adolescente , Adulto , Cesárea/mortalidad , Estudios Transversales , Países en Desarrollo , Femenino , Predicción , Humanos , Lactante , Cuidado del Lactante/estadística & datos numéricos , Recién Nacido , Kenia , Modelos Logísticos , Masculino , Persona de Mediana Edad , Oportunidad Relativa , Embarazo , Factores de Riesgo , Población Rural/estadística & datos numéricos , Encuestas y Cuestionarios , Tanzanía , Adulto Joven
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